Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of DNASE1L3 in human tissue homogenates, cell lysates.
Target Information: This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]